Vaccination provides protection from respiratory deterioration and death among hospitalized COVID-19 patients: Differences between vector and mRNA vaccinesArticle Published on 2022-06-012023-07-08 Journal: Journal of medical virology [Category] COVID19(2023년), [키워드] Astra Zeneca COVID-19 Moderna Pfizer SARS-CoV-2 vaccination. [DOI] 10.1002/jmv.27666 PMC 바로가기
Identification of B-Cell Epitopes for Eliciting Neutralizing Antibodies against the SARS-CoV-2 Spike Protein through Bioinformatics and Monoclonal Antibody Targeting생물정보학 및 단일클론 항체 표적화를 통한 SARS-CoV-2 스파이크 단백질에 대한 중화 항체 유도를 위한 B-세포 에피토프 식별Review Published on 2022-04-142022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 변종, 진단, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus adaptive Adaptive immunity Analysis antibody approach Astra Zeneca B cell B cells B-cell B-cell epitope B-cell epitopes caused cells complex coronavirus COVID-19 COVID-19 vaccine Critical effective Eliciting epitope Epitopes global public health Health crisis Hospitalization identification Immunity Impact in silico in vivo less linear B-cell epitope mapping membrane Moderna monoclonal antibodies monoclonal antibody multi-epitope peptide vaccine Neutralizing Neutralizing antibodies neutralizing antibody new SARS-CoV-2 nucleocapsid protein offer peptide Pfizer-BioNTech potent produced Protective provide reducing respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike Spike protein targeting the SARS-CoV-2 three-dimensional structure transmission of SARS-CoV-2 Vaccine vaccine. Vaccines variants virus virus viruses Wuhan strain [DOI] 10.3390/ijms23084341 PMC 바로가기 [Article Type] Review
Impact of prior vaccination with Covishield TM and Covaxin® on mortality among symptomatic COVID-19 patients during the second wave of the pandemic in South India during April and May 2021: a cohort study2021년 4월과 5월에 남인도에서 2차 대유행 기간 동안 Covishield TM 및 Covaxin®을 사용한 사전 예방 접종이 증상이 있는 COVID-19 환자의 사망률에 미치는 영향: 코호트 연구Article Published on 2022-03-182022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval Adjusted analysis Admission age Astra Zeneca circulation Cohort cohort study Corona Corona virus COVAXIN® COVID-19 COVID-19 patient COVID-19 patients COVID-19 vaccine COVID-19 vaccines COVISHIELDTM dose doses Emergency use evaluated expressed greater Hospitalization ICU ICU admission Impact impacted indeterminate India intensive care intensive care unit mitigate Mortality NIV non-invasive ventilation Oxford oxygen Oxygen therapy pandemic Patient patients presenting Primary outcome reduced risk risk ratio RT-PCR second wave severity severity of illness south India symptomatic vaccination vaccination. Vaccine variant were assessed widespread [DOI] 10.1016/j.vaccine.2022.02.023 PMC 바로가기 [Article Type] Article
Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccinationArticle Published on 2022-01-252023-06-16 Journal: Cell [Category] MERS, SARS, [키워드] antibodies Astra Zeneca Autopsy BBIBP-CorV BioNTech-Pfizer BNT162b2 ChAdOx1-S COVID-19 delta variant Endemic coronaviruses Gam-COVID-Vac Imprinting lymph node germinal center Moderna mRNA-1273 SARS-CoV-2 SARS-CoV-2 variants of concern Sinopharm Sputnik V Vaccine [DOI] 10.1016/j.cell.2022.01.018 PMC 바로가기 [Article Type] Article
IgG and IgA Antibodies Post SARS-CoV-2 Vaccine in the Breast Milk and Sera of Breastfeeding WomenArticle Published on 2022-01-162022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] absence Analysis anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG antibodies Astra Zeneca average Breast breast milk Breastfeeding carried changes in collected Complete COVID-19 COVID-19 pandemic decrease enrolled evaluate expected Fever first dose Health Health status IgA IgG IgG antibody immunological characteristics Infant information Intervention milk mitigate Moderna mother Neutralizing pandemic persistence Pfizer/BioNTech positive SARS-CoV-2 second dose sera serum Seven vaccination vaccination against COVID-19 Vaccine vaccine dose women [DOI] 10.3390/vaccines10010125 PMC 바로가기 [Article Type] Article
Reduced neutralisation of the Delta (B.1.617.2) SARS-CoV-2 variant of concern following vaccination델타의 중화 감소 (B.1.617.2) 예방 접종 후 SARS-COV-2 우려 변형Research Article Published on 2021-12-022022-08-13 Journal: PLoS Pathogens [Category] Biochemistry, SARS, 변종, 진단, [키워드] (Beta accumulation African antibody Antibody titre antigenic antigenic drift antigenic profiles assessment Astra Zeneca Author B.1.351 B.1.617.1 B.1.617.2 bat bats Beta BNT162b2 BNT162b2 vaccines Booster vaccine booster vaccines ChAdOx1 changes in collected COVID-19 COVID19 death decrease decreases Delta delta variant dose effective Effectiveness Efficacy elicited evade expressed facilitate fold Fold changes glycoprotein groups hospitalisation Human human cell human cells humans Immunity India indicated individual Infection Lineage magnitude Mutation neutralisation neutralise Neutralising Antibodies neutralising antibody titres of BNT162b2 Pfizer Pfizer/BioNTech Prevent profile protective immune response pseudoviruses recipient recipients reduced reduction reduction in reductions reductions in required risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 virus sensitivity sera Severe infection shape significantly higher South South Africa spike glycoprotein spike glycoproteins Spike protein subsequent the spike protein titre vaccinated individuals vaccination Vaccine vaccine efficacy Vaccines variant variant B.1.617.2 variants variants of concern Viral viral variant Viral variants virus Virus spike VOCs while with infection with infections Wuhan Wuhan, China [DOI] 10.1371/journal.ppat.1010022 PMC 바로가기 [Article Type] Research Article
First Report of Two Cases of Löfgren’s Syndrome after SARS-CoV-2 Vaccination-Coincidence or Causality?Case Report Published on 2021-11-112022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] addition association Astra Zeneca Clinical improvement Course COVID-19 de novo first symptom first vaccination Glucocorticoids Löfgren’s syndrome new coronavirus SARS-CoV-2 one patient Patient reaction report required sarcoidosis SARS-CoV-2 SARS-CoV-2 vaccination second vaccination Symptom syndrome Treatment vaccination Vaccine [DOI] 10.3390/vaccines9111313 PMC 바로가기 [Article Type] Case Report
438. Phenotypic Differences Between Distinct Immune Biomarker Clusters During the ‘Hyperinflammatory’ Middle-Phase of COVID-19Poster Abstracts Published on 2021-11-042022-10-29 Journal: Open Forum Infectious Diseases [Category] COVID-19, [키워드] acute respiratory syndrome adjusted age Algorithm Analysis approach association Astra Zeneca AstraZeneca Bar baseline Biomarker Bonferroni-corrected chronic pulmonary disease Cluster Clustering Clusters collected comorbid disease coronavirus COVID-19 COVID-19 cohort COVID-19 vaccine COVID19 Cutoff Data analysis diabete difference disease evaluated female figure Fisher’s exact test Frequency hospital hospitalized patients identify immunoassay individuals with COVID-19 Infection Inflammation inflammation marker Inflammatory Kruskal-Wallis test Logistic regression Lung disease machine material median Mild obesity offer Other performed phase Plasma level positive post-symptom onset Prevalence prevalent Prognosis Protein Result risk factor SARS-CoV-2 SARS-CoV-2 RT-PCR selected sensitivity analysis severity significance level specimen steroid treatment subject Support table The United States therapy topological data analysis Trial unique was performed was used were measured with COVID-19 [DOI] 10.1093/ofid/ofab466.637 PMC 바로가기 [Article Type] Poster Abstracts
Coagulopathies after Vaccination against SARS-CoV-2 May Be Derived from a Combined Effect of SARS-CoV-2 Spike Protein and Adenovirus Vector-Triggered Signaling PathwaysSARS-CoV-2에 대한 백신 접종 후 응고증은 SARS-CoV-2 스파이크 단백질과 아데노바이러스 벡터 유발 신호 경로의 결합 효과에서 파생될 수 있음Review Published on 2021-10-062022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 유전자 메커니즘, [키워드] adenoviral vector adenoviral vector vaccine adenoviral vector-based vaccines Antigen applied approved Astra Zeneca cellular mechanism ChAdOx1 ChAdOx1 nCoV-19 Coagulopathies Combined component coronavirus SARS-CoV-2 correlated Coverage COVID-19 death Effect effort global pandemic herd immunity hypothese hypotheses Hypothesis immune systems Immunity immunization inactivated infection rate molecular molecular mechanism mRNA NF-kappaB novel Novel coronavirus novel coronavirus SARS-CoV-2 platelet factor 4 (PF4) Prevalence reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine SARS-CoV-2 virus Side effect Side effects spike Spike protein Spread statistical the vaccine thrombocytopenia thrombosis vaccination Vaccine vaccine-induced immune thrombotic thrombocytopenia (VITT) Viral viral vectors [DOI] 10.3390/ijms221910791 PMC 바로가기 [Article Type] Review
Post SARS-CoV-2 vaccination Guillain-Barre syndrome in 19 patientsReview Article Published on 2021-09-282022-10-31 Journal: Clinics [Category] COVID-19, MERS, SARS, [키워드] age applied article Astra Zeneca complications COVID-19 develop Evidence female first dose Guillain-barrè syndrome Johnson & Johnson latency male mechanical ventilation Mild moderate neuro-COVID nine Patient patients Pfizer Polyradiculitis ranged recovered completely required Research SARS-CoV-2 SARS-CoV-2 vaccination Side effect Side effects steroid syndrome the vaccine therapy Treatment vaccination Vaccine was used [DOI] 10.6061/clinics/2021/e3286 PMC 바로가기 [Article Type] Review Article